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PUBLICATIONS

For a full and updated list of publications, please see Google Scholar.

Publications including and after 2023, Tep lab members are in bold

2026

Image by National Cancer Institute

Strengthening Antisense Oligonucleotide-Mediated Anti-Tumor Immunity via Metal-Organic Framework Nanoparticles

Nowak, J. A., Cho, E., Davis, M. A., Zheng, S., Bell, L., Sha, F., Magdalenski, J. S., Lui, A., Napoli, M., Falahat, R., Mulé, J.J., Flores, E.R., Farha, O. K., Teplensky, M.H. Nano Lett. 2026.

2025

Image by National Institute of Allergy and Infectious Diseases

Modulating antigen processing through metal–organic frameworks to bias adaptive immunity

Cho, E., Davis, M. A., Nowak, J. A., Izzo, M., Ferrante, A., Sha, F., Magdalenski, J. S., Farha, O. K., Teplensky, M.H. PNAS. 2025. 122 (45), e2409555122.

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Structural immunotherapy: Harnessing chemical design to build powerful next-generation therapeutics

Teplensky, M.H., Bourgeois, J. N.; Kudruk, S.; Hurst Petrosko, S.; Mirkin, C. A. PNAS. 2025. 122 (45), e2409553122.

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33 Unresolved Questions in Nanoscience and Nanotechnology

Mirkin, C. A.; Petrosko, S. H.; [...] Teplensky, M. H.; [...] et al. ACS Nano. 2025, 19 (36), 31933–31968.

2023

Harnessing Biomaterial Architecture to Drive Anticancer Innate Immunity

Davis, M. A.*, Cho, E.* Teplensky, M.H. J. Mat. Chem. B 2023. 11, 10982 - 11005.

*Co-authors

Image by National Cancer Institute

Rational vaccinology maximizes the efficacy of multi-antigen vaccines

Mirkin, C.A and Teplensky, M.H. Nat. Biomed. Eng. 2023, 7, 851 - 852.

Prior to BU

Mapping the position of genes in the cell nucleus sheds light on basic principles governin

Controlling Intracellular Processing to Enhance Spherical Nucleic Acids Immune Stimulation

Kang, J., Teplensky, M. H., Dittmar, J., Evangelopoulos, M., Hwang, J., Mirkin, C.A. PNAS. 2025. 122 (45), e2409554122

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Tuning DNA Dissociation from Spherical Nucleic Acids for Enhanced Immunostimulation

Dittmar, J.W., Teplensky, M.H., Evangelopoulos, M., Qin, L., Zhang, B., Mirkin, C. A. ACS Nano. 2023. 17 (18), 17996–18007.

Molecule

Molecular DNA Dendron Vaccines

Distler, M. E.*, Cavaliere, J.*, Teplensky, M.H., Evangelopoulos, M., Mirkin, C. A. Proc. Natl. Acad. Sci. 2023. 120 (5) e2215091120.

*Co-authors

Multi-antigen Spherical Nucleic Acids Cancer Vaccines

Teplensky, M.H.*, Evangelopoulos, M.*, Dittmar, J., Forsyth, C. M., Sinegra, A.J.; Wang, S., Mirkin, C.A. Nat. Biomed. Eng. 2023. 7, 911 - 927.

*Co-authors

Green Pattern

Controlling Intracellular Machinery via Polymer Pen Lithography Molecular Patterning

Lin, M.*; Meckes, B.*; Chen, C.; Teplensky, M. H.; Mirkin, C. A. ACS Cent. Sci. 2022, 8 (9), 1282-1289.

*Co-authors

Green Pattern

Modular nucleic acid scaffolds for synthesizing monodisperse and sequence-encoded antibody oligomers

Winegar, P. H.*; Figg, C. A.*; Teplensky, M. H.; Ramani, N.; Mirkin, C. A. Chem 2022. 8 (11), 3018-3030.

*Co-authors

Image by CDC

Spherical nucleic acids as an infectious disease vaccine platform

Teplensky, M. H.*; Distler, M. E.*; Kusmierz, C. D.; Evangelopoulos, M.; Gula, H.; Elli, D.; Tomatsidou, A.; Nicolaescu, V.; Gelarden, I.; Yeldandi, A.; Batlle, D.; Missiakas, D.; Mirkin, C. A. Proc. Natl. Acad. Sci. 2022, 119 (14).

*Co-authors

Image by National Cancer Institute

Chemically Tuning the Antigen Release Kinetics from Spherical Nucleic Acids Maximizes Immune Stimulation

Skakuj, K.; Teplensky, M. H.; Wang, S.; Dittmar, J. W.; Mirkin, C. A. ACS Cent. Sci. 2021, 7 (11), 1838–1846.

Image by Braňo

DNA dendrons as agents for intracellular delivery

Distler, M. E.; Teplensky, M. H.; Bujold, K. E.; Kusmierz, C. D.; Evangelopoulos, M.; Mirkin, C. A. J. Am. Chem. Soc. 2021, 143 (34), 13513–13518.

Image by National Cancer Institute

Spherical Nucleic Acid Vaccine Structure Markedly Influences Adaptive Immune Responses of Clinically Utilized Prostate Cancer Targets

Teplensky, M. H.; Dittmar, J. W.; Qin, L.; Wang, S.; Evangelopoulos, M.; Zhang, B.; Mirkin, C. A. Adv. Healthc. Mater. 2021, 2101262.

Image by Sangharsh Lohakare

A highly porous metal-organic framework system to deliver payloads for gene knockdown

Teplensky, M. H.; Fantham, M.; Poudel, C.; Hockings, C.; Lu, M.; Guna, A.; Aragones-Anglada, M.; Moghadam, P. Z.; Li, P.; Farha, O. K.; Bernaldo de Quirós Fernández, S.; Richards, F. M.; Jodrell, D. I.; Kaminski Schierle, G.; Kaminski, C. F.; Fairen-Jimenez, D. Chem 2019, 5 (11), 2926–2941.

Temperature treatment of highly porous zirconium-containing metal–organic frameworks extends drug delivery release

Teplensky, M. H.; Fantham, M.; Li, P.; Wang, T. C.; Mehta, J. P.; Young, L. J.; Moghadam, P. Z.; Hupp, J. T.; Farha, O. K.; Kaminski, C. F.; Fairen-Jimenez, D. J. Am. Chem. Soc. 2017, 139 (22), 7522–7532.

Image by Sigmund

Metal-Organic Frameworks as Biosensors for Luminescence-Based Detection and Imaging

Miller, S. E.*; Teplensky, M. H.*; Moghadam, P. Z.; Fairen-Jimenez, D. Interface Focus 2016, 6 (4), 1–14.

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